Updated evaluation (Oct. 2015) of the genetic toxicology of tert-butanol (TBA) and tert-Butyl acetate (TBAC)
نویسنده
چکیده
The overall response to TBA and TBAC in genetic toxicology assays is very weak to negative. There are only three papers that are relevant to TBA with purported positive responses. These results are far out-numbered by negative results in the mouse lymphoma assay, Chinese hamster ovary assessment for SCEs, aberrations and micronuclei, and negative responses in Salmonella TA 98, 100, 104, 1535, and 1537. The overall data supports a negative overall assessment of genotoxicity for TBA and TBAC (see below and Tables 1 & 2).
منابع مشابه
Gene mdpC plays a regulatory role in the methyl-tert-butyl ether degradation pathway of Methylibium petroleiphilum strain PM1.
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